This racial group includes any of the original peoples of North, South and Central America who maintain tribal affiliation or community attachment. The five leading causes of death among American Indians and Alaska Natives are heart disease, cancer, unintentional injuries, diabetes and chronic liver disease/cirrhosis, according to the U.S. Centers for Disease Control & Prevention's Office of Minority Health & Health Disparities. Native Americans suffer disproportionately high rates of obesity, infant mortality, mental health problems and substance abuse.